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KMID : 0043320120350122127
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Archives of Pharmacal Research
2012 Volume.35 No. 12 p.2127 ~ p.2133
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Four new antioxidant phenylpropanoid glycosides from Microlepia pilosissima
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Hu Jiang
Shi Xiaodong
Chen Jiangang
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Abstract
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Four new phenylpropanoid glycosides, 9-O-[β-D-glucopyranosyl-(1→2)-α-L-rhamnopyranosyl]-3,4-dimethoxy-cinnamic acid (1), 9-O-[β-D-glucopyranosyl-(1→2)-α-L-rhamnopyranosyl]-4-methoxycinnamic acid (2), 9-O-α-L-rhamnopyranosyl-3,4-dimethoxy-cinnamic acid (3), and 9-O-[6-Oacetyl-β-D-glucopyranosyl]-4-methoxy-cinnamic acid (4), together with three known compounds 9-O-α-L-rhamnopyranosyl-4-hydroxy-cinnamic acid (5), 9-O-β-D-glucopyranosyl-4-methoxycinnamic acid (6), and 9-O-β-D-glucopyranosyl-3,4-dimethoxy-cinnamic acid (7) were isolated from the 70% EtOH extract of the dry fronds of Microlepia pilosissima. Their chemical structures were elucidated by spectroscopic analysis. Moreover, 1 and 2 exhibited comparable scavenging activities with (±)-α-tocopherol against DPPH radicals, while compounds 3?7 displayed moderate antioxidant activities.
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KEYWORD
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Microlepia pilosissima, Dennstaedtiaceae, Phenylpropanoid glycoside, Antioxidant activity
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